Begin by degreasing the lesion with a defatting solution, such as alcohol or acetone. The lesion is then treated with a direct cryotherapy application, holding the device 4 mm above the skin at a 90° angle.
A light white frost indicates effective freezing. After the first freeze, allow the tissue to thaw for 30 seconds before applying a second freeze. Mild redness may appear as part of the normal inflammatory response.
Sebaceous hyperplasia typically resolves within 14 days, leaving healthy skin underneath.